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Five Ss were tested on nine occasions under two placebos of tap water and under an average effective dose of 7 drugs--ergometerine (Ergonovine), ethyl alcohol, scopolamine (hyroscine), d-1-brom lysergic acid diethylamide (BOL-148), methamphetamine hydrochloride (Methedrine or Pervitin), lysergic acid monoethylamide (LAE-32), and lysergic acid diethylamide (LSD-25) during 9 different experimental sessions . . ... The Ss completed a questionnaire inquiring about their perceptual, physiological and cognitive state before they received the drug or placebo and .5, 2.5 and 4.5 hours after receiving it . . ... Although differentiation between 3 lysergic acid derivatives, Ergonovine, LAE-32, and BOL-148, and between alcohol, methamphetamine, and scopolamine was not clear cut, the number of responses to the questionnaire under these drugs was clearly greater than those given under water . . ... LSD-25 clearly produced the most frequent and the largest positive responses. (PsycINFO Database Record (c) 2006 APA, all rights reserved)
Jarvik et al. (Tue,) studied this question.