Surgical intervention for laryngeal sarcomas yielded a 5-year overall survival of 76% and disease-specific survival of 90%.
Observational (n=10)
No
What are the treatment outcomes of surgical intervention in patients with laryngeal sarcoma?
Surgical intervention for laryngeal sarcoma yields a relatively good prognosis with a 5-year overall survival of 76%.
BACKGROUND: Sarcomas of the larynx are rare neoplasms that constitute less than 1% of laryngeal malignancies. A Medline search found no large series focusing on laryngeal sarcomas. We reviewed the cases of laryngeal sarcomas treated in our cancer center and compared our experiences and treatment results with those from other centers. METHODS: A retrospective review of 10 patients with laryngeal sarcoma treated in our institute between 1980 and 2000 was done to identify tumor characteristics, therapeutic modalities, and treatment outcomes. RESULTS: The patients showed a male predominance (9/10) and presented 8 types of pathology. Nine patients underwent surgery, including 2 total laryngectomy, 4 partial laryngectomy, and 3 endoscopic laser cordectomy. During a median follow-up of 92 months, the 5-year overall survival and disease-specific survival were 76% and 90%, respectively. Two patients developed recurrence, including 1 local recurrence and 1 distant metastasis. CONCLUSION: Surgical intervention was the first choice in the treatment of laryngeal sarcomas. The prognosis is relatively good when compared with sarcoma originating from other anatomic sites.
Liu et al. (Wed,) conducted a observational in Laryngeal sarcoma (n=10). Surgical intervention was evaluated on 5-year overall survival. Surgical intervention for laryngeal sarcomas yielded a 5-year overall survival of 76% and disease-specific survival of 90%.