Does routine manual thrombectomy reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure in patients with STEMI undergoing primary PCI?
Patients with STEMI who were undergoing primary PCI
Routine manual thrombectomy
PCI alone
Composite of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 dayscomposite
Routine manual thrombectomy during primary PCI for STEMI does not improve 180-day clinical outcomes and is associated with an increased risk of early stroke.
In patients with STEMI who were undergoing primary PCI, routine manual thrombectomy, as compared with PCI alone, did not reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 days but was associated with an increased rate of stroke within 30 days. (Funded by Medtronic and the Canadian Institutes of Health Research; TOTAL ClinicalTrials.gov number, NCT01149044.).
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Sanjit S. Jolly
Interventional Cardiology
John A. Cairns
General Cardiology
Salim Yusuf
Population Health Research Institute
New England Journal of Medicine
Inserm
University of British Columbia
Université Paris Cité
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Jolly et al. (Mon,) studied this question.
synapsesocial.com/papers/69d56e2975589c71d767d459 — DOI: https://doi.org/10.1056/nejmoa1415098