Why the study?
Does routine manual thrombectomy reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure in patients with STEMI undergoing primary PCI?
Does routine manual thrombectomy reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure in patients with STEMI undergoing primary PCI?
Routine manual thrombectomy during primary PCI for STEMI does not improve 180-day clinical outcomes and is associated with an increased risk of early stroke.
Routine manual thrombectomy should not be used in primary PCI for STEMI; confirms neutral primary outcomes with stroke signal in this RCT.
In patients with STEMI who were undergoing primary PCI, routine manual thrombectomy, as compared with PCI alone, did not reduce the risk of cardiovascular death, recurrent myocardial infarction, cardiogenic shock, or NYHA class IV heart failure within 180 days but was associated with an increased rate of stroke within 30 days. (Funded by Medtronic and the Canadian Institutes of Health Research; TOTAL ClinicalTrials.gov number, NCT01149044.).
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Jolly et al. (2015) studied this question.
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