May 5, 2008Open Access
Results of the Predictors of Response to CRT (PROSPECT) Trial
Structured PICO
Do echocardiographic measures of dyssynchrony improve patient selection for CRT beyond current guidelines?
P
Population
Patients evaluated for cardiac resynchronization therapy (CRT)
I
Intervention
Echocardiographic measures of dyssynchrony
O
Outcome
Response to CRT
No single echocardiographic measure of dyssynchrony is currently recommended to improve patient selection for CRT beyond standard guidelines due to high variability.
Abstract
Given the modest sensitivity and specificity in this multicenter setting despite training and central analysis, no single echocardiographic measure of dyssynchrony may be recommended to improve patient selection for CRT beyond current guidelines. Efforts aimed at reducing variability arising from technical and interpretative factors may improve the predictive power of these echocardiographic parameters in a broad clinical setting.
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Authors
E
Eugene Chung
Christ Hospital
A
Angel R. León
Electrophysiology
Luigi Tavazzi
Heart Failure & Transplant
Journals
Circulation
Actions
Institutions
The Ohio State University
References and Citations
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