Does an algorithm incorporating hs-cTnT baseline values and absolute changes within the first hour allow safe rule-out and accurate rule-in of AMI in unselected patients with acute chest pain?
A 1-hour hs-cTnT algorithm can successfully triage approximately 77% of patients presenting with acute chest pain, potentially obviating the need for prolonged monitoring and serial blood sampling.
Using a simple algorithm incorporating hs-cTnT baseline values and absolute changes within the first hour allowed a safe rule-out as well as an accurate rule-in of AMI within 1 hour in 77% of unselected patients with acute chest pain. This novel strategy may obviate the need for prolonged monitoring and serial blood sampling in 3 of 4 patients.
Reichlin et al. (Mon,) studied this question.