Reduction in Inappropriate Therapy and Mortality through ICD Programming

Structured PICO

Does high-rate or delayed ICD programming reduce inappropriate therapy and all-cause mortality compared with conventional programming?

Population

Patients receiving implantable cardioverter-defibrillator (ICD) therapies

Intervention

Programming of ICD therapies for tachyarrhythmias of 200 beats per minute or higher or with a prolonged delay in therapy at 170 beats per minute or higher

Comparator

Conventional programming

Outcome

Inappropriate therapy and all-cause mortality during long-term follow-uphard clinical

Programming ICDs for higher rate thresholds or prolonged delays safely reduces inappropriate therapies and improves overall survival compared to conventional programming.

Abstract

Programming of ICD therapies for tachyarrhythmias of 200 beats per minute or higher or with a prolonged delay in therapy at 170 beats per minute or higher, as compared with conventional programming, was associated with reductions in inappropriate therapy and all-cause mortality during long-term follow-up. (Funded by Boston Scientific; MADIT-RIT ClinicalTrials.gov number, NCT00947310.).

Reduction in Inappropriate Therapy and Mortality through ICD Programming

Structured PICO

Abstract

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Also Consider