Patients with heart failure and a normal ejection fraction
The pathophysiological cause of elevated diastolic pressures and heart failure in patients with normal ejection fraction is abnormal diastolic function.
Patients with heart failure and a normal ejection fraction have significant abnormalities in active relaxation and passive stiffness. In these patients, the pathophysiological cause of elevated diastolic pressures and heart failure is abnormal diastolic function.
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Michael R. Zile
Heart Failure & Transplant
Catalin F. Baicu
Heart Failure & Transplant
William H. Gaasch
Heart Failure & Transplant
New England Journal of Medicine
University of Massachusetts Chan Medical School
Medical University of South Carolina
Lahey Hospital and Medical Center
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Zile et al. (Wed,) studied this question.
synapsesocial.com/papers/69dea3dfaa033a6615558360 — DOI: https://doi.org/10.1056/nejmoa032566