Diastolic Heart Failure — Abnormalities in Active Relaxation and Passive Stiffness of the Left Ventricle
Population
Patients with heart failure and a normal ejection fraction
Design
Review
Authors
Discussion
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Member takes
Implication
Abnormal diastolic function explains HFpEF symptoms; leaves open targeted therapies for relaxation and stiffness.
Structured PICO
P
Population
Patients with heart failure and a normal ejection fraction
The pathophysiological cause of elevated diastolic pressures and heart failure in patients with normal ejection fraction is abnormal diastolic function.
Cite This Study
Zile et al. (2004) studied this question.