eNOS deficiency in mice is strongly associated with the development of a bicuspid aortic valve, providing molecular insight into this common congenital cardiac abnormality.
These results show a strong association between eNOS deficiency and the presence of a bicuspid aortic valve; they provide the first molecular insight into one of the most common types of congenital cardiac abnormality.
Lee et al. (Tue,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: