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Our study shows that low LBM is a significant predictor of toxicity in female patients administered 5-FU using the convention of dosing per unit of body surface area. We conclude that variation in toxicity between females and males may be partially explained by this feature of body composition.
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Carla M. Prado
Vickie E. Baracos
Linda J. McCargar
Clinical Cancer Research
University of Alberta
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Prado et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69d8565fd56ca42147d186a5 — DOI: https://doi.org/10.1158/1078-0432.ccr-06-3067
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