Does spironolactone improve survival and reduce hypokalemia in patients with severe heart failure?
Patients with severe heart failure
Spironolactone
Hypokalemia and survivalhard clinical
Spironolactone use is associated with improved survival and less hypokalemia in severe heart failure, provided appropriate surveillance of potassium and creatinine is maintained.
With appropriate surveillance of potassium and creatinine, the use of spironolactone was associated with less hypokalemia and improved survival in patients with severe heart failure even in the setting of moderate hyperkalemia.
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Orly Vardeny
Brian Claggett
Inder S. Anand
Circulation Heart Failure
University of Wisconsin–Madison
Inserm
University of Minnesota
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Vardeny et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69d8f9576715230d10bede13 — DOI: https://doi.org/10.1161/circheartfailure.114.001104