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One-year MM survival has increased for all age groups during the last decades; 5-year and 10-year MM survival has increased in younger patients (younger than 60 to 70 years). High-dose melphalan with subsequent autologous stem-cell transplantation, thalidomide, and a continuous improvement in supportive care measures are probably the most important factors contributing to this finding. New effective agents with a more favorable toxicity profile are needed to improve survival further, particularly in the elderly.
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Kristinsson et al. (Tue,) studied this question.
synapsesocial.com/papers/69c9f1a241c9e32f2f00da3c — DOI: https://doi.org/10.1200/jco.2006.09.0100
Sigurður Y. Kristinsson
Reykjavík University
Ola Landgren
BC Cancer Agency
Paul W. Dickman
Karolinska Institutet
Journal of Clinical Oncology
National Cancer Institute
Karolinska University Hospital
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