Free-breathing cine-GRICS cardiac MRI yielded similar volumetric parameters compared to a standard breath-held protocol, with differences of 3% ± 2.4 in the LV and 2.9% ± 4.4 in the RV.
Observational (n=6)
Does free-breathing cardiac MRI using 2D cine-GRICS provide comparable assessment of cardiac function to standard breath-held protocols in human subjects?
Free-breathing cine-GRICS MRI provides accurate assessment of cardiac volumes and function comparable to standard breath-held protocols, offering a motion-corrected alternative.
PURPOSE: To assess cardiac function by means of a novel free-breathing cardiac magnetic resonance imaging (MRI) strategy. MATERIALS AND METHODS: A stack of ungated 2D steady-state free precession (SSFP) slices was acquired during free breathing and reconstructed as cardiac cine imaging based on the generalized reconstruction by inversion of coupled systems (GRICS). A motion-compensated sliding window approach allows reconstructing cine movies with most motion artifacts cancelled. The proposed reconstruction uses prior knowledge from respiratory belts and electrocardiogram recordings and features a piecewise linear model that relates the electrocardiogram signal to cardiac displacements. The free-breathing protocol was validated in six subjects against a standard breath-held protocol. RESULTS: Image sharpness, as assessed by the image gradient entropy, was comparable to that of breath-held images and significantly better than in uncorrected images. Volumetric parameters of cardiac function in the left ventricle (LV) and right ventricle (RV) were similar, including end-systolic volumes, end-diastolic volumes and mass, stroke volumes, and ejection fractions (with differences of 3% ± 2.4 in the LV and 2.9% ± 4.4 in the RV). The duration of the free-breathing protocol was nearly the same as the breath-held protocol. CONCLUSION: Free-breathing cine-GRICS enables accurate assessment of volumetric parameters of cardiac function with efficient correction of motion.
Vuissoz et al. (Tue,) reported a observational. Free-breathing 2D cine-GRICS cardiac MRI vs. Standard breath-held protocol was evaluated on Volumetric parameters of cardiac function (LV and RV). Free-breathing cine-GRICS cardiac MRI yielded similar volumetric parameters compared to a standard breath-held protocol, with differences of 3% ± 2.4 in the LV and 2.9% ± 4.4 in the RV.