Does selective endothelin-A receptor antagonism prevent prolonged endothelial dysfunction induced by mental stress?
Selective endothelin-A receptor antagonism
Prolonged endothelial dysfunctionsurrogate
Selective endothelin-A receptor antagonism prevents mental stress-induced prolonged endothelial dysfunction, providing a novel link to atherosclerotic vascular disease.
Mental stress induces prolonged endothelial dysfunction, which is prevented by selective endothelin-A receptor antagonism. This represents a novel and important link between mental stress and atherosclerotic vascular disease.
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Lukas E. Spieker
David Hürlimann
Frank Ruschitzka
Circulation
University Hospital of Bern
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Spieker et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69c30281a77124f241cab4f6 — DOI: https://doi.org/10.1161/01.cir.0000021598.15895.34