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December 26, 2007New England Journal of MedicineOpen Access

Prophylactic Catheter Ablation for the Prevention of Defibrillator Therapy

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Why the study?

Does prophylactic substrate-based catheter ablation reduce the incidence of ICD therapy in patients with a history of myocardial infarction who received ICDs for the secondary prevention of sudden death?

Population

Patients with a history of myocardial infarction who received ICDs for the secondary prevention of sudden…

Design

RCT, Randomized

Authors

VRVivek Y. ReddyMRMatthew R. ReynoldsPNPetr Neužil

Discussion

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Overview

Supports prophylactic ablation to reduce ICD therapies in post-MI secondary prevention; extends substrate-based evidence to randomized setting.

Key Points

  • To evaluate the effectiveness of prophylactic catheter ablation in reducing ICD therapy for patients with a history of myocardial infarction.
  • Randomized trial design
  • Patients with myocardial infarction received ICDs for secondary prevention
  • Prophylactic substrate-based catheter ablation was performed
  • Catheter ablation significantly reduced the incidence of ICD therapy in the tested population

Structured PICO

Does prophylactic substrate-based catheter ablation reduce the incidence of ICD therapy in patients with a history of myocardial infarction who received ICDs for the secondary prevention of sudden death?

P
Population
Patients with a history of myocardial infarction who received ICDs for the secondary prevention of sudden death
I
Intervention
Prophylactic substrate-based catheter ablation
O
Outcome
Incidence of ICD therapy

Prophylactic substrate-based catheter ablation reduces the incidence of ICD therapy in patients with prior MI receiving ICDs for secondary prevention.

Cite This Study

Reddy et al. (2007) studied this question.

synapsesocial.com/papers/69dea73b4838c5c0bab0c82bhttps://doi.org/10.1056/nejmoa065457
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