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Abstract Fluorescent background is a major problem in recoding the Raman spectra of many samples, which swamps or obscures the Raman signals. The background should be suppressed in order to perform further qualitative or quantitative analysis of the spectra. For this purpose, an intelligent background‐correction algorithm is developed, which simulates manual background‐correction procedure intelligently. It basically consists of three aspects: (1) accurate peak position detection in the Raman spectrum by continuous wavelet transform (CWT) with the Mexican Hat wavelet as the mother wavelet; (2) peak‐width estimation by signal‐to‐noise ratio (SNR) enhancing derivative calculation based on CWT but with the Haar wavelet as the mother wavelet; and (3) background fitting using penalized least squares with binary masks. This algorithm does not require any preprocessing step for transforming the spectrum into the wavelet space and can suppress the fluorescent background of Raman spectra intelligently and validly. The algorithm is implemented in R language and available as open source software ( http://code.google.com/p/baselinewavelet ). Copyright © 2009 John Wiley & Sons, Ltd.
Zhang et al. (Fri,) studied this question.
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