Do ACE inhibitors improve outcomes compared to diuretics in older subjects with hypertension?
Older subjects with hypertension
Angiotensin-Converting-Enzyme (ACE) inhibitors
Diuretic agents
Outcomes (not further specified)
ACE inhibitors may provide better clinical outcomes than diuretics in older hypertensive patients, especially men, independent of the degree of blood pressure reduction.
Initiation of antihypertensive treatment involving ACE inhibitors in older subjects, particularly men, appears to lead to better outcomes than treatment with diuretic agents, despite similar reductions of blood pressure.
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Lindon M.H. Wing
Christopher M. Reid
Philip Ryan
New England Journal of Medicine
The University of Melbourne
The University of Queensland
UNSW Sydney
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Wing et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d6adc275cae9790bed887f — DOI: https://doi.org/10.1056/nejmoa021716