November 19, 2013

In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the ATHEROREMO-IVUS study

Structured PICO

Does the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery predict MACE within 1 year in patients undergoing coronary angiography?

P

Population

Patients undergoing coronary angiography

I

Intervention

Presence of IVUS virtual histology-derived thin-cap fibroatheroma (TCFA) lesions in a non-culprit coronary artery

C

Comparator

Absence of TCFA lesions or presence of small TCFA lesions

O

Outcome

Occurrence of major adverse cardiac events (MACE) within 1 year, particularly death and acute coronary syndrome (ACS)composite

IVUS virtual histology-derived thin-cap fibroatheroma lesions in non-culprit arteries independently predict 1-year MACE, death, and ACS in patients undergoing coronary angiography.

Abstract

In patients undergoing coronary angiography, the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery is strongly and independently predictive for the occurrence of MACE within 1 year, particularly of death and ACS. Thin-cap fibroatheroma lesions with a large plaque burden carry higher risk than small TCFA lesions, especially on the short term.

In vivo detection of high-risk coronary plaques by radiofrequency intravascular ultrasound and cardiovascular outcome: results of the ATHEROREMO-IVUS study

Structured PICO

Abstract

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