Why the study?
The prognostic value of IVUS virtual histology-derived thin-cap fibroatheroma lesions in non-culprit coronary arteries for predicting MACE was not fully established.
Does the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery predict MACE within 1 year in patients undergoing coronary angiography?
Does the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery predict MACE within 1 year in patients undergoing coronary angiography?
IVUS virtual histology-derived thin-cap fibroatheroma lesions in non-culprit arteries independently predict 1-year MACE, death, and ACS in patients undergoing coronary angiography.
In patients undergoing coronary angiography, the presence of IVUS virtual histology-derived TCFA lesions in a non-culprit coronary artery is strongly and independently predictive for the occurrence of MACE within 1 year, particularly of death and ACS. Thin-cap fibroatheroma lesions with a large plaque burden carry higher risk than small TCFA lesions, especially on the short term.
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Cheng et al. (2013) studied this question.
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