Application of 35 mmHg lower body positive pressure during dynamic exercise augmented the release of arginine vasopressin and catecholamines, but not plasma renin activity.
Does moderate muscle metaboreflex activation via lower body positive pressure augment the release of arginine vasopressin, plasma renin activity, and catecholamines during dynamic exercise in healthy adults?
Moderate activation of the muscle metaboreflex during dynamic exercise augments the release of arginine vasopressin and catecholamines, but not plasma renin activity, suggesting non-uniform thresholds for hormonal responses.
We examined the hypothesis that activation of the muscle metaboreflex during dynamic exercise would augment influences tending to cause a rise in arginine vasopressin, plasma renin activity, and catecholamines during dynamic exercise in humans. Ten healthy adults performed 30 min of supine cycle ergometer exercise at ∼50% of peak oxygen consumption with or without moderate muscle metaboreflex activation by application of 35 mmHg lower body positive pressure (LBPP). Application of LBPP during the first 15 or last 15 min of exercise increased mean arterial blood pressure, plasma lactate concentration, and minute ventilation, indicating an activation of the muscle metaboreflex. These changes were rapidly reversed when LBPP was removed. During exercise at this intensity, LBPP augmented the release of arginine vasopressin and catecholamines but not of plasma renin activity. These results suggest that, although in humans hormonal responses are induced by moderate activation of the muscle metaboreflex during dynamic exercise, the thresholds for these responses may not be uniform among the various glands and hormones.
Nishiyasu et al. (Sat,) conducted a other in Healthy adults (n=10). Lower body positive pressure (LBPP) vs. Exercise without LBPP was evaluated on Arginine vasopressin, plasma renin activity, and catecholamines. Application of 35 mmHg lower body positive pressure during dynamic exercise augmented the release of arginine vasopressin and catecholamines, but not plasma renin activity.