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A means is developed whereby coordinate sets for related molecules may be compared in such a way as to express rigorously the relationship between them in terms of position, orientation, homogeneous strain and curvature. It is thought that such curvatures may be of value in characterizing hinge regions of allosteric enzymes. The method is illustrated with examples taken from haemoglobin and myoglobin.
Robert M. Diamond (Thu,) studied this question.