Nr4a1 plays a crucial role in regulating the inflammatory and reparative functions of Ly-6C(high) monocytes following myocardial infarction.
Ly-6C(high) monocytes orchestrate both inflammatory and reparative phases during myocardial infarction and depend on Nr4a1 to limit their influx and inflammatory cytokine expression.
Hilgendorf et al. (Fri,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: