What question did this study set out to answer?

To evaluate how physical conditioning affects haemostatic and haemorheological responses to strenuous maximal exercise.

November 1, 1987Journal of International Medical Research14 citations

Response of Some Haemocoagulatory and Haemorheological Variables to Maximal Exercise in Sedentary and Active Subjects

MSM. De Scalzi PCP Cinelli VLVittorio de Leonardis

Key Points

To evaluate how physical conditioning affects haemostatic and haemorheological responses to strenuous maximal exercise.
Assessed 25 male participants stratified into sedentary (n=14) and active (n=11) groups.
Administered a graded bicycle ergometer test with an initial 25 W workload increasing by 25 W every 3 minutes.
Measured platelet count, platelet aggregability, plasma fibrinogen, fibrinolytic degradation products, blood viscosity, and micro-haematocrit before and after exercise.
Baseline differences between the sedentary and active cohorts were statistically significant only for blood viscosity.
Strenuous exercise significantly increased platelet count, fibrinolytic degradation products, blood viscosity, and micro-haematocrit across both groups.
Platelet aggregability and plasma fibrinogen levels showed no significant change after exercise in either group.

Abstract

The purpose of this study was to evaluate how physical conditioning is associated with haemostatic and rheological responses to strenuous exercise. A total of 25 males, divided into two groups differing in exercise fitness (14 sedentary and 11 active), underwent exercise testing on a bicycle ergometer with an initial 25 W workload increasing by the same amount every 3 min. The following variables were evaluated before and after the test: platelet count and aggregability, plasma fibrinogen, fibrinolytic degradation products, viscometry and micro-haematocrit. Significant differences in baseline values between the two groups were found only for blood viscosity. Irrespective of the group, significantly increased values were demonstrated for all the variables, except platelet aggregability and fibrinogen levels, in response to strenuous exercise. It is concluded that the possible protective effect of exercise against cardiovascular disease does not seem to be related to changes in the haemorheological and haemostatic measures evaluated.

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