September 18, 2009CHEST Journal6,793 citationsOpen Access
View Full PaperRefining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach
Key Result
The novel risk factor-based stroke risk stratification schema improved predictive value for thromboembolism compared to the CHADS(2) schema in atrial fibrillation patients.
Structured PICO
Does a novel risk factor-based schema improve prediction of stroke and thromboembolism compared to the CHADS(2) schema in patients with atrial fibrillation?
P
Population
Patients with atrial fibrillation (AF)
I
Intervention
Novel risk factor-based stroke risk stratification schema
C
Comparator
CHADS(2) schema
O
Outcome
Stroke and thromboembolism (TE)hard clinical
A novel risk factor-based stratification schema improves the prediction of stroke and thromboembolism over the traditional CHADS(2) score in patients with atrial fibrillation.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
Our novel, simple stroke risk stratification schema, based on a risk factor approach, provides some improvement in predictive value for TE over the CHADS(2) schema, with low event rates in low-risk subjects and the classification of only a small proportion of subjects into the intermediate-risk category. This schema could improve our approach to stroke risk stratification in patients with AF.