Does carotid-wall intima-media thickness measurement improve the classification of risk of cardiovascular disease in the Framingham Offspring Study cohort?
Framingham Offspring Study cohort
Measurement of maximum internal and mean common carotid-artery intima-media thickness and presence of plaque
Cardiovascular outcomes and classification of risk of cardiovascular diseasehard clinical
Maximum internal carotid artery intima-media thickness and plaque presence modestly improve cardiovascular risk classification.
The maximum internal and mean common carotid-artery intima-media thicknesses both predict cardiovascular outcomes, but only the maximum intima-media thickness of (and presence of plaque in) the internal carotid artery significantly (albeit modestly) improves the classification of risk of cardiovascular disease in the Framingham Offspring Study cohort. (Funded by the National Heart, Lung, and Blood Institute.).
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Joseph F. Polak
Michael Pencina
Karol M. Pencina
New England Journal of Medicine
Boston University
National Heart Lung and Blood Institute
Tufts Medical Center
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Polak et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69dd358b7808b00a4799b709 — DOI: https://doi.org/10.1056/nejmoa1012592
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