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Silencing of MALAT1 tips the balance from a proliferative to a migratory endothelial cell phenotype in vitro, and its genetic deletion or pharmacological inhibition reduces vascular growth in vivo.
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Katharina Michalik
Xintian You
Yosif Manavski
Circulation Research
Max Planck Institute for Heart and Lung Research
Georg Speyer Haus
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Michalik et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69deefd0488ed2d92be944ab — DOI: https://doi.org/10.1161/circresaha.114.303265