Does low-dose systemic alteplase (tPA) provide safe and effective treatment in patients with acute pulmonary embolism?
Low-dose systemic tPA may be a safe and effective treatment for acute pulmonary embolism, especially in patients at high risk of bleeding.
The available data suggest that low-dose tPA may be a safe and effective treatment option for acute PE, particularly in patients at a high risk of bleeding. More studies are needed to determine the optimal dosing regimen of tPA for PE.
Brandt et al. (Thu,) studied this question.