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We identified a novel mechanism by which tumor immune evasion is regulated by p53/miR-34/PDL1 axis. Our results suggest that delivery of miRNAs with standard therapies, such as XRT, may represent a novel therapeutic approach for lung cancer.
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María Angélica Cortez
Cristina Ivan
David R. Valdecanas
JNCI Journal of the National Cancer Institute
The Ohio State University
The University of Texas MD Anderson Cancer Center
Mirna Therapeutics (United States)
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Cortez et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d99ff8e6ab964fb083601c — DOI: https://doi.org/10.1093/jnci/djv303
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