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November 17, 2015JNCI Journal of the National Cancer Institute690 citationsOpen Access

PDL1 Regulation by p53 via miR-34

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MCMaría Angélica CortezCICristina IvanDVDavid R. Valdecanas

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Abstract

We identified a novel mechanism by which tumor immune evasion is regulated by p53/miR-34/PDL1 axis. Our results suggest that delivery of miRNAs with standard therapies, such as XRT, may represent a novel therapeutic approach for lung cancer.

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Cortez et al. (2015) studied this question.

synapsesocial.com/papers/69d99ff8e6ab964fb083601chttps://doi.org/10.1093/jnci/djv303
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