Do SOFA and qSOFA scores accurately predict in-hospital mortality in patients with suspected infection compared to LODS and SIRS?
Encounters with suspected infection (both ICU and outside of the ICU)
SOFA score (ICU) and qSOFA score (outside ICU)
LODS and SIRS scores
Predictive validity for in-hospital mortalityhard clinical
SOFA is superior for predicting mortality in ICU patients with suspected infection, whereas qSOFA is superior for non-ICU patients.
Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis. Among encounters with suspected infection outside of the ICU, the predictive validity for in-hospital mortality of qSOFA was statistically greater than SOFA and SIRS, supporting its use as a prompt to consider possible sepsis.
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Christopher W. Seymour
Jean‐Louis Vincent
Theodore J. Iwashyna
JAMA
University of Washington
University of Michigan
University of Toronto
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Seymour et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d737213f2a6ac123b8a796 — DOI: https://doi.org/10.1001/jama.2016.0288