Why the study?
Do SOFA and qSOFA scores accurately predict in-hospital mortality in patients with suspected infection compared to LODS and SIRS?
Do SOFA and qSOFA scores accurately predict in-hospital mortality in patients with suspected infection compared to LODS and SIRS?
SOFA is superior for predicting mortality in ICU patients with suspected infection, whereas qSOFA is superior for non-ICU patients.
Supports SOFA for ICU and qSOFA for non-ICU mortality prediction in suspected infection; leaves open prospective validation before practice change.
Among ICU encounters with suspected infection, the predictive validity for in-hospital mortality of SOFA was not significantly different than the more complex LODS but was statistically greater than SIRS and qSOFA, supporting its use in clinical criteria for sepsis. Among encounters with suspected infection outside of the ICU, the predictive validity for in-hospital mortality of qSOFA was statistically greater than SOFA and SIRS, supporting its use as a prompt to consider possible sepsis.
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Seymour et al. (2016) studied this question.
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