Moderate-intensity aerobic exercise after a first myocardial infarction significantly reduced left ventricular mass from 128.7 to 117.2 g (p=0.0032) and improved the LVmass/EDV ratio (p=0.015).
Does moderate intensity aerobic exercise improve ventricular remodeling evaluated by CMR in male patients after a first myocardial infarction?
Moderate intensity aerobic exercise for at least 3 months after a first myocardial infarction improves physical capacity and induces positive ventricular remodeling characterized by reduced left ventricular mass.
p-value: p=0.015
BACKGROUND: Numerous studies show the benefits of exercise training after myocardial infarction (MI). Nevertheless, the effects on function and remodeling are still controversial. OBJECTIVES: To evaluate, in patients after (MI), the effects of aerobic exercise of moderate intensity on ventricular remodeling by cardiac magnetic resonance imaging (CMR). METHODS: 26 male patients, 52.9 ± 7.9 years, after a first MI, were assigned to groups: trained group (TG), 18; and control group (CG), 8. The TG performed supervised aerobic exercise on treadmill twice a week, and unsupervised sessions on 2 additional days per week, for at least 3 months. Laboratory tests, anthropometric measurements, resting heart rate (HR), exercise test, and CMR were conducted at baseline and follow-up. RESULTS: The TG showed a 10.8% reduction in fasting blood glucose (p = 0.01), and a 7.3-bpm reduction in resting HR in both sitting and supine positions (p < 0.0001). There was an increase in oxygen uptake only in the TG (35.4 ± 8.1 to 49.1 ± 9.6 mL/kg/min, p < 0.0001). There was a statistically significant decrease in the TG left ventricular mass (LVmass) (128.7 ± 38.9 to 117.2 ± 27.2 g, p = 0.0032). There were no statistically significant changes in the values of left ventricular end-diastolic volume (LVEDV) and ejection fraction in the groups. The LVmass/EDV ratio demonstrated a statistically significant positive remodeling in the TG (p = 0.015). CONCLUSIONS: Aerobic exercise of moderate intensity improved physical capacity and other cardiovascular variables. A positive remodeling was identified in the TG, where a left ventricular diastolic dimension increase was associated with LVmass reduction.
Izeli et al. (Fri,) conducted a other in Myocardial Infarction (n=26). Aerobic exercise of moderate intensity vs. Control group was evaluated on Ventricular remodeling (LVmass/EDV ratio) (p=0.015). Moderate-intensity aerobic exercise after a first myocardial infarction significantly reduced left ventricular mass from 128.7 to 117.2 g (p=0.0032) and improved the LVmass/EDV ratio (p=0.015).
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