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A Method for the Selective Hydrogenation of Alkenyl Halides to Alkyl Halides | Synapse

April 30, 2014

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A Method for the Selective Hydrogenation of Alkenyl Halides to Alkyl Halides

SKSandra M. KingIIT@MIT XMXiaoshen MaMerck & Co., Inc., Rahway, NJ, USA (United States)SHSeth B. HerzonYale University

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Abstract

A general method for the selective hydrogenation of alkenyl halides to alkyl halides is described. Fluoro, chloro, bromo, iodo, and gem-dihaloalkenes are viable substrates for the transformation. The selectivity of the hydrogenation is consistent with reduction by a hydrogen atom transfer pathway.

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King et al. (Wed,) studied this question.

synapsesocial.com/papers/6a0868eb113ba5b476de24d8 https://doi.org/https://doi.org/10.1021/ja502885c

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