Tenascin C upregulates IL-6 expression in human cardiac myofibroblasts via the TLR4 receptor, providing mechanistic insight into cardiac inflammation and fibrosis.
TNC up-regulates IL-6 expression in human CMF, an effect mediated through the FBG domain of TNC and via the TLR4 receptor.
Maqbool et al. (Fri,) studied this question.