Coronary occlusion in unanesthetized dogs resulted in an overpayment of flow debt during reactive hyperemia averaging 500 ± 200%, driven independently by occlusion duration and control flow rate.
Myocardial reactive hyperemia
Coronary occlusion
Volume of reactive hyperemia flow
Studies of myocardial reactive hyperemia in dogs 5–24 days after the implantation of electromagnetic flowmeters on coronary artery branches reveal that the duration of occlusion and the control flow rate are independent determinants of the volume of reactive hyperemia flow. Flow debt is almost always overpaid, the average figure being 500 ± 200%. Phasic coronary flow curves show an increase in both systolic and diastolic flow during reactive hyperemia, the increase in systolic flow being due in part to decreased myocardial contractility. Myocardial reactive hyperemia is thought to be due to the accumulation of vasodilator metabolites during the period of coronary occlusion.
Building similarity graph...
Analyzing shared references across papers
Loading...
Ray A. Olsson
Forschungszentrum Jülich
Donald E. Gregg
Walter Reed Army Institute of Research
American Journal of Physiology-Legacy Content
Walter Reed Army Institute of Research
Building similarity graph...
Analyzing shared references across papers
Loading...
Olsson et al. (Mon,) conducted a other in Myocardial reactive hyperemia. Coronary occlusion was evaluated on Volume of reactive hyperemia flow. Coronary occlusion in unanesthetized dogs resulted in an overpayment of flow debt during reactive hyperemia averaging 500 ± 200%, driven independently by occlusion duration and control flow rate.
synapsesocial.com/papers/6a0d642748a82a5ce309b6d7 — DOI: https://doi.org/10.1152/ajplegacy.1965.208.2.224
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: