Key points are not available for this paper at this time.
The robust capacity of antioxidant pretreatment to delay fatigue provides compelling evidence that ROS play a causal role in this process. There are caveats to this story of course, issues related to the type of antioxidant and mode of administration. Also, the translation of this laboratory concept into clinical practice has been slow. Still, antioxidant therapy has the potential to benefit individuals who experience premature fatigue and this remains a promising area for future research.
Michael B. Reid (Fri,) studied this question.