Alcohol consumption was associated with a higher rate of atrial fibrillation recurrence after initial catheter ablation compared to no alcohol consumption (41.9% vs 34.1%; P=0.003).
Cohort (n=1,361)
Does alcohol consumption affect atrial fibrillation recurrence after catheter ablation in patients with paroxysmal atrial fibrillation?
More frequent alcohol consumption is associated with a higher risk of atrial fibrillation recurrence after initial catheter ablation, highlighting the importance of lifestyle modification in AF management.
Effect estimate: HR 1.07 per 1 day/week increase (95% CI 1.00-1.15)
Absolute Event Rate: 41.9% vs 34.1%
p-value: p=0.003
BACKGROUND: Although several studies have reported an association between atrial fibrillation (AF) and alcohol, the impact of alcohol consumption on the outcome after catheter ablation (CA) for AF has not been discussed. We aimed to elucidate the effect of alcohol consumption on the outcome of CA for paroxysmal AF. METHODS AND RESULTS: We examined 1361 consecutive patients with paroxysmal AF (mean age, 61±11 years, 334 women) who underwent CA, including 623 (45.8%) patients who consumed alcohol. The clinical characteristics and outcomes of CA were compared between patients who did and did not consume alcohol. No significant differences were seen in the left atrial size, duration of AF history, and incidence of nonpulmonary vein foci between 2 groups (P=NS). Although the AF recurrence-free rate after the initial CA was higher in patients who did not consume alcohol (261/623 41.9% versus 252/738 34.1%; mean follow-up, 44.4±30.7 months; P=0.003), the outcome after the final CA was similar between 2 groups (patients who consumed alcohol: 111/628 17.7% versus patients who did not consume alcohol: 138/738 18.7%; mean follow-up, 53.1±25.8 months; P=0.67). The frequency (hazard ratio 1.07 per 1 day/week increase, CI 1.00-1.15, P=0.04) of alcohol consumption was significantly associated with AF recurrence after CA. CONCLUSIONS: The frequency of alcohol consumption may be associated with AF recurrence after the initial CA for paroxysmal AF, but it may not affect the outcome after the final CA.
Takigawa et al. (Tue,) conducted a cohort in Paroxysmal atrial fibrillation (n=1,361). Alcohol consumption vs. No alcohol consumption was evaluated on Atrial fibrillation recurrence after the initial catheter ablation (HR 1.07 per 1 day/week increase, 95% CI 1.00-1.15, p=0.003). Alcohol consumption was associated with a higher rate of atrial fibrillation recurrence after initial catheter ablation compared to no alcohol consumption (41.9% vs 34.1%; P=0.003).