High-intensity interval training improved cardiometabolic risk factors in type 2 diabetes, but these benefits were not augmented by the addition of post-exercise milk or protein.
RCT (n=53)
Double-blind
Variable permuted block sizes with computer-generated random numbers
No
Does post-exercise milk or protein consumption augment the cardiometabolic benefits of high-intensity interval training (HIIT) in adults with type 2 diabetes?
p-value: p=0.74
Background: High-intensity interval training (HIIT) can improve several aspects of cardiometabolic health. Previous studies have suggested that adaptations to exercise training can be augmented with post-exercise milk or protein consumption, but whether this nutritional strategy can impact the cardiometabolic adaptations to HIIT in type 2 diabetes is unknown. Objective: To determine if the addition of a post-exercise milk or protein beverage to a high-intensity interval training (HIIT) intervention improves cardiometabolic health in individuals with type 2 diabetes. Design: In a proof-of-concept, double-blind clinical trial 53 adults with uncomplicated type 2 diabetes were randomized to one of three nutritional beverages (500 mL skim-milk, macronutrient control or flavored water placebo) consumed after exercise (3 days/wk) during a 12 week low-volume HIIT intervention. HIIT involved 10 X 1-min high-intensity intervals separated by 1-min low-intensity recovery periods. Two sessions per week were cardio-based (at ~90% of heart rate max) and one session involved resistance-based exercises (at RPE of 5-6; CR-10 scale) in the same interval pattern. Continuous glucose monitoring (CGM), glycosylated hemoglobin (HbA1c), body composition (dual-energy X-ray absorptiometry), cardiorespiratory fitness (V̇O2peak), blood pressure and endothelial function (%FMD) were measured before and after the intervention. Results: There were significant main effects of time (all p0.71) for CGM 24-h mean glucose (-0.5 ± 1.1 mmol/L), HbA1c (-0.2 ± 0.4%), percent body fat (-0.8 ± 1.6%), and lean mass (+1.1 ± 2.8 kg). Similarly, V̇O2peak (+2.5 ± 1.6 mL/kg/min) and %FMD (+1.4 ± 1.9%) were increased, and mean arterial blood pressure reduced (-6 ± 7 mmHg), after 12 weeks of HIIT (all p0.11). Conclusion: High-intensity interval training is a potent stimulus for improving several important metabolic and cardiovascular risk factors in type 2 diabetes. The benefits of HIIT are not augmented by the addition of post-exercise protein.
François et al. (Tue,) conducted a rct in Type 2 Diabetes (n=53). Post-exercise milk or protein beverage vs. Flavored water placebo was evaluated on 24-h average glucose (p=0.74). High-intensity interval training improved cardiometabolic risk factors in type 2 diabetes, but these benefits were not augmented by the addition of post-exercise milk or protein.
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