May 1, 1971Open Access
View Full PaperOpen‐Loop Analysis of the Renin‐Angiotensin System in the Dog
Structured PICO
P
Population
Dogs in which the cardiovascular control loops of the central nervous system were eliminated by spinal cord destruction and decapitation
I
Intervention
Open-loop analysis of the renin-angiotensin system
O
Outcome
Loop gain and time response of the renin-angiotensin systemsurrogate
This preclinical study determined the loop gain and time response of the renin-angiotensin system in a canine model without central nervous system cardiovascular control.
Abstract
The loop gain and time response of the renin-angiotensin system was determined in dogs in which the cardiovascular control loops of the central nervous system were eliminated by spinal cord destruction and decapitation.