Does dual-chamber pacing with closed loop stimulation reduce syncope burden and time to first recurrence in patients age ≥40 years with head-up tilt test-induced vasovagal syncope?
Dual-chamber pacing with closed loop stimulation significantly reduces syncope burden and delays recurrence in older patients with tilt-induced vasovagal syncope.
DDD-CLS pacing significantly reduced syncope burden and time to first recurrence by 7-fold, prolonging time to first syncope recurrence in patients age ≥40 years with head-up tilt test-induced vasovagal syncope compared with sham pacing. (Closed Loop Stimulation for Neuromediated Syncope SPAIN Study; NCT01621464).
Barón‐Esquivias et al. (Mon,) studied this question.