October 25, 2017Open Access

Glycation Reduces the Stability of ApoAI and Increases HDL Dysfunction in Diet-Controlled Type 2 Diabetes

SKSangeeta R. KashyapNew York Proton Center AÖAbdullah ÖsmeCase Western Reserve University SISerguei IlchenkoNortheast Ohio Medical University

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Abstract

The 2H2O method allowed the detection of early in vivo impairments in HDL metabolism and function that were related to hyperglycemia-induced glycation of ApoAI in T2DM.

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Kashyap et al. (Wed,) studied this question.

synapsesocial.com/papers/69dcc4331e43378fbd1332eb https://doi.org/https://doi.org/10.1210/jc.2017-01551

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