December 6, 2017Open Access
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
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Abstract
We identified 64 novel genetic risk loci for CAD and performed fine mapping of all 161 risk loci to obtain a credible set of causal variants. The large expansion of reconstituted gene sets argues in favor of an expanded omnigenic model view on the genetic architecture of CAD.
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Authors
Pim van der Harst
Interventional Cardiology
Niek Verweij
Preventive Cardiology
Journals
Circulation Research
Actions
Institutions
Netherlands Heart Institute
References and Citations
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