Identifies specific macrophage subpopulation shifts, specifically increased CCR2+ monocytes and CD206+ macrophages, associated with myxomatous valve disease.
Our study demonstrates the heterogeneity of myeloid cells in heart valves and highlights an alteration of macrophage subpopulations, notably an increased presence of infiltrating CCR2+ monocytes and CD206+ macrophages, in myxomatous valve disease.
Hulin et al. (Thu,) studied this question.
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