Obesity surgery significantly reduced obesity-related co-morbidities over 5 years, halving diabetes-related hyperglycemia, with a morbidity of 3.1% and in-hospital mortality of 0.07%.
Observational
Yes
Does obesity surgery improve obesity-related co-morbidities in a real-world UK population?
Real-world data from the UK National Bariatric Surgery Registry demonstrates that obesity surgery safely and substantially improves multiple obesity-related comorbidities, including diabetes and hypertension, over 5 years.
BACKGROUND: The National Bariatric Surgery Registry (NBSR) is the largest bespoke database in the field in the United Kingdom. OBJECTIVES: Our aim was to analyze the NBSR to determine whether the effects of obesity surgery on associated co-morbidities observed in small randomized controlled clinical trials could be replicated in a "real life" setting within U.K. healthcare. SETTING: United Kingdom. METHODS: All NBSR entries for operations between 2000 and 2015 with associated demographic and co-morbidity data were analyzed retrospectively. RESULTS: . Over 5 years of follow-up, statistically significant reductions in the prevalence of type 2 diabetes, hypertension, dyslipidemia, sleep apnea, asthma, functional impairment, arthritis, and gastroesophageal reflux disease were observed. The "remission" of these co-morbidities was evident 1 year postoperatively and reached a plateau 2 to 5 years after surgery. Obesity surgery was particularly effective on functional impairment and diabetes, almost doubling the proportion of patients able to climb 3 flights of stairs and halving the proportion of patients with diabetes related hyperglycemia compared with preoperatively. Surgery was safe with a morbidity of 3.1% and in-hospital mortality of .07% and a reduced median inpatient stay of 2 days, despite an increasingly sick patient population. CONCLUSIONS: Obesity surgery in the U.K. results not only in weight loss, but also in substantial improvements in obesity-related co-morbidities. Appropriate support and funding will help improve the quality of the NBSR data set even further, thus enabling its use to inform healthcare policy.
Miras et al. (2018) conducted an observational in Obesity. Obesity surgery vs. Preoperative baseline was evaluated on Prevalence of obesity-related co-morbidities. Obesity surgery significantly reduced obesity-related co-morbidities over 5 years, halving diabetes-related hyperglycemia, with a morbidity of 3.1% and in-hospital mortality of 0.07%.