June 4, 2018Open Access
Therapeutic Attenuation of Cardiac Remodeling After Acute Myocardial Infarction
Key Result
Research on the renin-angiotensin-aldosterone system and adrenergic mechanisms provided the foundation for therapeutic attenuation of cardiac remodeling after acute myocardial infarction.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
Dr Rutherford asks: In the early 1970s, you, and your late wife Janice, studied adrenergic mechanisms and cardiac hypertrophy and ventricular function, as well, in spontaneously hypertensive rats. What led to your initial animal studies on acute myocardial infarction and your interest in the renin-angiotensin-aldosterone system?
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Authors
Marc A. Pfeffer
Heart Failure & Transplant
J
John D. Rutherford
General Cardiology
Journals
Circulation
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