Does acute exposure to IQOS aerosol impair vascular endothelial function in rats compared to cigarette smoke?
rats
Acute exposure to aerosol from a single IQOS HeatStick
Cigarette smoke
Vascular endothelial function (flow-mediated dilation / FMD)surrogate
Acute exposure to IQOS aerosol impairs vascular endothelial function in a rat model similarly to cigarette smoke, suggesting it may not avoid the adverse cardiovascular effects of smoking.
Acute exposures to IQOS aerosol impairs FMD in rats. IQOS use does not necessarily avoid the adverse cardiovascular effects of smoking cigarettes.
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Pooneh Nabavizadeh
University of California, San Francisco
Jiangtao Liu
Harbin Medical University
Christopher Havel
Lawrence Berkeley National Laboratory
Tobacco Control
University of California, San Francisco
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Nabavizadeh et al. (Tue,) studied this question.
synapsesocial.com/papers/69da2ee20d540cafc5838d0e — DOI: https://doi.org/10.1136/tobaccocontrol-2018-054325