October 3, 2018Open Access
Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics
Structured PICO
What are the outcomes and high-risk predictors for mortality in patients with asymptomatic aortic stenosis followed up in heart valve clinics?
P
Population
Patients with asymptomatic aortic stenosis (AS) followed up in heart valve centers
I
Intervention
Follow-up in heart valve clinics (with potential subsequent aortic valve replacement)
O
Outcome
Sudden death, overall survival, all-cause mortality, and cardiovascular mortalityhard clinical
Patients with asymptomatic severe AS and high-risk features (peak velocity ≥5.0 m/s or LVEF <60%) have increased mortality risk even after AVR, suggesting a potential benefit for early intervention.
Abstract
In patients with asymptomatic AS followed up in heart valve centers, the risk of sudden death is low, and rates of overall survival are similar to those reported from previous series. Patients with severe AS at baseline and peak aortic jet velocity of 5.0 m/s or greater or LVEF less than 60% have increased risks of all-cause and cardiovascular mortality even after AVR. The potential benefit of early intervention should be considered in these high-risk patients.
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Authors
Patrizio Lancellotti
Structural Heart Disease
J
Julien Magné
Cardiac Imaging
R
Raluca Dulgheru
Cardiac Imaging
Journals
JAMA Cardiology
Actions
Institutions
Inserm
Leiden University Medical Center
Université Laval
References and Citations
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