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What are the outcomes and high-risk predictors for mortality in patients with asymptomatic aortic stenosis followed up in heart valve clinics?
What are the outcomes and high-risk predictors for mortality in patients with asymptomatic aortic stenosis followed up in heart valve clinics?
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Patients with asymptomatic severe AS and high-risk features (peak velocity ≥5.0 m/s or LVEF <60%) have increased mortality risk even after AVR, suggesting a potential benefit for early intervention.
In patients with asymptomatic AS followed up in heart valve centers, the risk of sudden death is low, and rates of overall survival are similar to those reported from previous series. Patients with severe AS at baseline and peak aortic jet velocity of 5.0 m/s or greater or LVEF less than 60% have increased risks of all-cause and cardiovascular mortality even after AVR. The potential benefit of early intervention should be considered in these high-risk patients.
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Lancellotti et al. (2018) studied this question.
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