Multigenic causation and bilineal inheritance in dilated cardiomyopathy may occur at a higher frequency than previously anticipated, highlighting its genetic heterogeneity.
Dilated cardiomyopathy can have multigenic causation, suggesting that genetic heterogeneity in DCM is more common than previously thought.
Absolute Event Rate: 0% vs 0%
BACKGROUND: variant. We hypothesized that additional genetic cause may underlie DCM in these families. METHODS: variants. RESULTS: variant. CONCLUSIONS: Our data support DCM as a genetically heterogeneous disease with, at times, multigene causation. Although the frequency of DCM resulting from multigenic cause is uncertain, our data suggest it may be higher than previously anticipated.
Cowan et al. (Sun,) reported a other. Multigenic causation and bilineal inheritance in dilated cardiomyopathy may occur at a higher frequency than previously anticipated, highlighting its genetic heterogeneity.